{"id":2704,"date":"2025-10-22T14:34:36","date_gmt":"2025-10-22T14:34:36","guid":{"rendered":"https:\/\/alipanc.org\/?p=2704"},"modified":"2025-10-22T14:34:36","modified_gmt":"2025-10-22T14:34:36","slug":"alipanc-researchers-contribute-to-the-successful-launch-of-the-first-digestive-disease-mechanisms-ddm-summit-at-ueg-week-2025","status":"publish","type":"post","link":"https:\/\/alipanc.org\/en\/alipanc-researchers-contribute-to-the-successful-launch-of-the-first-digestive-disease-mechanisms-ddm-summit-at-ueg-week-2025\/","title":{"rendered":"ALIPANC Researchers Contribute to the Successful Launch of the First Digestive Disease Mechanisms (DDM) Summit at UEG Week 2025"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-2705 alignleft\" src=\"https:\/\/alipanc.org\/wp-content\/uploads\/UEG-300x300.jpeg\" alt=\"\" width=\"300\" height=\"300\" \/>On October 5\u20137, 2025, the annual <strong>United European\u00a0<\/strong><strong>Gastroenterology (UEG) Week<\/strong> in Berlin hosted the inaugural <strong>Digestive Disease Mechanisms (DDM) Summit<\/strong>, organized by <strong>Francisco X. Real<\/strong>, <strong>Mathias Heikenw\u00e4lder<\/strong>, and <strong>Maria Sibilia<\/strong>. The DDM Summit marked the first <strong>basic research\u2013focused program<\/strong> within UEG Week, which has traditionally been recognized for its clinical orientation. This new initiative aims to <strong>bridge the gap between clinicians and scientists<\/strong>, fostering translational collaboration across the fields of <strong>gastroenterology, hepatology, and pancreatic research<\/strong>.<\/p>\n<p>The <strong>ALIPANC consortium<\/strong> was represented in Berlin by <strong>Francisco X. Real<\/strong>, <strong>N\u00faria Malats<\/strong>, <strong>Chengsi Wu<\/strong>, and <strong>Mikhail Chesnokov<\/strong>. <strong>Chengsi Wu<\/strong> delivered an oral presentation on how gut microbiome dynamics shape pancreatic health in the context of <em>Nr5a2<\/em> gene haploinsufficiency, presenting new evidence that microbiome-targeted strategies could offer preventive opportunities for pancreatic disease. <strong>Mikhail Chesnokov<\/strong> presented a poster revealing a novel role of the transcription factor NR5A2 in the regulation of intestinal epithelial cell fate and colon homeostasis. In recognition of their contributions, both researchers received <strong>travel grants<\/strong> to attend the summit, and <strong>Chengsi Wu<\/strong> was appointed as chair of the \u201cImmune Mechanisms in Gastrointestinal Diseases\u201d session.<\/p>\n<p>The <strong>DDM Summit<\/strong> brought together leading experts in pancreatic disease research, including <strong>Grainne O\u2019Kane, Dieter Saur, Laura Machesky, Andreas Trumpp,<\/strong> and <strong>Tuomas Tammela<\/strong>. Other Spanish scientists, including <strong>Eduard Batlle (IRB Barcelona)<\/strong>, <strong>Nabil Djouder (CNIO)<\/strong>, and <strong>Guadalupe Sabio (CNIO)<\/strong> delivered invited talks on colorectal and liver cancer.<\/p>\n<p>The event fostered a productive exchange between clinicians and basic researchers, highlighting the growing integration of scientific discovery and medical practice within the UEG community.<\/p>\n<p>Through its active participation, <strong>ALIPANC<\/strong> reaffirmed its commitment to <strong>supporting early-career scientists<\/strong> and promoting excellence in <strong>basic and translational research<\/strong> on the mechanisms underlying pancreatic disease. Following its successful debut, the <a href=\"https:\/\/ueg.eu\/week\/programme\/ddm-summit\">DDM Summit<\/a> is expected to become a regular feature of future UEG Week meetings.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>On October 5\u20137, 2025, the annual United European\u00a0Gastroenterology (UEG) Week in Berlin hosted the inaugural Digestive Disease Mechanisms (DDM) Summit, organized by Francisco X. Real, Mathias Heikenw\u00e4lder, and Maria Sibilia. The DDM Summit marked the first basic research\u2013focused program within UEG Week, which has traditionally been recognized for its clinical orientation. This new initiative aims [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2704","post","type-post","status-publish","format-standard","hentry","category-sin-categorizar"],"_links":{"self":[{"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/posts\/2704","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/comments?post=2704"}],"version-history":[{"count":4,"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/posts\/2704\/revisions"}],"predecessor-version":[{"id":2714,"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/posts\/2704\/revisions\/2714"}],"wp:attachment":[{"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/media?parent=2704"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/categories?post=2704"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/alipanc.org\/en\/wp-json\/wp\/v2\/tags?post=2704"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}