At the CNIO’s Metabolism and Cell Signaling laboratory we study the connection between nutrient excess and cancer. In particular, pancreatic cancer has a strong association with an elevated body mass index, and we still largely do not know why this association exists. Using mouse models, together with biochemical and cellular tools, our group focuses on understanding how overweight leads to aberrant activation of the immune system, chronic inflammation and cellular alterations in the pancreatic epithelium favor cancer development.
Neoantigens and Cancer Vaccines – Núria de la Iglesia
The Neoantigens and Cancer Vaccines group (NeoVaCan) is part of the IrsiCaixa Institute for Research on Immunopathologies, a center dedicated to the study of diseasesrelated to the immune system, ranging from viral infections, such as HIV or SARS-CoV-2, to cancer. Our...