Pancreas regeneration
Basic/translational research
Bellvitge Institute for Biomedical Research (IDIBELL)
·Barcelona ·

Our team studies the biology of normal pancreatic tissue as essential knowledge for understanding the cellular and medical “drama” associated with the development of pancreatic cancer. Specifically, we study ductal cells and the role they play in pancreatic regeneration and exocrine pathogenesis, including pancreatic cancer. The main project we have related to PDAC is focused on the cell of origin. We have generated new lineage-tracing mouse lines from previously unknown ductal populations to study the early stages and development of ductal-derived pancreatic tumors and define early biomarkers and novel therapies by using in vivo and organoid models of mouse and human PDAC samples.

Main publications in pancreatic cancer:

  1. PMID: 34330784

Principal Investigator

Group members

Joan Casamitjana (postdoc)

Ángel Fernández (PhD student)

Adrián Holguín (PhD student)

Marina Bermúdez (técnico de laboratorio)

Cecilia Chambers (postdoc, empieza en julio)

Joel Moro (bioinformatician, empieza en julio)

Other groups