The pancreatic cancer research group at IDIBAPS-Clinic Barcelona is a multidisciplinary group that brings together researchers with very complementary profiles and experiences ranging from clinical research, in its multiple specialties, to basic research.
The main lines of research of the group are focused on:
To deepen the pathophysiological knowledge of pancreatic cancer and to understand the underlying molecular mechanisms. We are interested in advancing our understanding of the involvement of the pancreatic stroma in carcinogenesis and especially in the cross-talk between neoplastic cell and tumor fibroblasts.
2. Discovery of new biomarkers for diagnosis, prognosis and predictive of survival or response to treatment.
3. Development of organoid models from surgical specimens and endoscopically guided biopsy. Establishment of more complex 3D culture models including tumor organoids and stromal cells.
4. Development of experimental therapies and preclinical studies in ex vivo and animal models. Therapies based on oncolytic virotherapy or nano-immunomedicines.
5. Innovation in endoscopic and surgical techniques to advance diagnosis and treatment.