Precision Nutrition and Cancer Laboratory /Molecular Oncology Group
Basic/translational research
Madrid Institute for Advanced Studies (IMDEA). Feeding
·Madrid ·

The Precision Nutrition and Cancer laboratory, headed by Dr. Ramirez de Molina focuses on improving the quality of life of cancer patients by designing precision nutrition products and strategies to improve tumor treatment and prognosis, as well as nutritional strategies to improve immune system impairment. The Precision Nutrition group is focused on studying the relationship between precision nutrition, metabolism and cancer. His group develops multidisciplinary research focused on: exploring metabolic reprogramming as a biomarker and therapeutic target in cancer; the study of the relationship between lifestyle factors (nutrition, physical activity), genetics (individual susceptibility), the consequent global metabolic state (healthy/unhealthy), its relationship with chronic inflammation and immune response, and the development, progression and response to treatment of cancer patients.

He is also involved in the development and application of digital systems and mhealth platforms to enable the exchange of key clinical prognostic data (patient symptoms, genetics, nutritional lifestyle factors…) between oncologists and patients, which are improving medical decision making by optimizing cancer treatment. In short, its main objective is to include precision nutrition in personalized medicine by analyzing personal characteristics, genetic susceptibility and physiological conditions, the microbiome, etc. to define biomarkers and personalized nutritional strategies that are effective in promoting health through molecular nutrition.

Main publications in pancreatic cancer:

  1. Fernández LP, Deleyto-Seldas N, Colmenarejo G, et al. Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3' untranslated region. Genome Biol. 2022 Oct 31;23(1):230. doi: 10.1186/s13059-022-02798-5. PMID: 36316722; PMCID: PMC9620695.
  2. Gómez de Cedrón M, Mouhid L, García-Carrascosa E, et al. Marigold Supercritical Extract as Potential Co-adjuvant in Pancreatic Cancer: The Energetic Catastrophe Induced via BMP8B Ends Up With Autophagy-Induced Cell Death. Front Bioeng Biotechnol. 2020 Jan 24;7:455. doi: 10.3389/fbioe.2019.00455. PMID: 32039173; PMCID: PMC6992545.
  3. Barradas M, Plaza A, Colmenarejo G, et al. PJ. Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity. Nat Commun. 2022 Sep 27;13(1):5677. doi: 10.1038/s41467-022-33352-3. PMID: 36167809; PMCID: PMC9515185.
Ana Ramírez de Molina
Lara Fernandez

Principal Investigator

Group members

  • Ana Ramírez de Molina
  • Lara Fernández
  • Marta Gómez de Cedrón
  • Cristina María Fernández
  • Silvia Cruz Gil

Other groups

Angiogenesis Group – Alfredo Martínez Ramírez

The Angiogenesis Group is part of the Oncology Area of the Biomedical Research Center of La Rioja (CIBIR), located in Logroño, Spain. As the name implies, the Angiogenesis Group focuses on the process of angiogenesis in relation to cancer and other relevant diseases...