The Translational Research Unit (UIT) group is made up of translational and clinical research personnel, and has the facilities and equipment necessary to design and execute translational biomedical research projects in the lines established as priorities at the General University Hospital of Ciudad Real (HGUCR), among which the following stand out: 1) Obesity, eating disorders and food addiction; 2) Oncology (chemohyperthermia, new chemotherapeutic dosage formats, new drug combinations, tumor stem cells, miRNAs); 3) Sepsis and septic shock; 4) Biological evaluation of active principles of plant origin; 5) Non-melanoma skin cancer and cutaneous cancerization field; and 6) Study of epidermal barrier function and development of new drugs for the treatment of chronic inflammatory dermatoses and scarring. In addition, the ITU is designed to provide instrumental and scientific support to clinical researchers who require it, for which it has the necessary technology to carry out molecular and cellular biology studies in vivo and in vitro, as well as histological studies, experimental behavioral analysis and disease modeling in rodents.

The ITU also participates in projects, agreements and research contracts with external public and private entities, and collaborates with the teaching, dissemination and care activities of the HGUCR within its scope of action.

In the field of pancreatic cancer, there are several lines of work among which we can highlight:

• Study of a new therapeutic model characterized by the application of Hyperthermic Intraabdominal Chemotherapy (HIPEC) with gemcitabine in patients with pancreatic ductal adenocarcinoma.
• Study of pancreatic tumor stem cells: isolation, search for new markers and new targeted therapies.