Pancreatic cancer research group
Basic/translational research
INCLIVA Health Research Institute. University of Valencia
·Valencia ·

The pancreatic cancer research group of our institution is mainly composed of researchers from the areas of Oncology (clinical and basic-translational), General Surgery and Anatomic Pathology. The main objective of the group is to increase the knowledge of the disease in order to develop new diagnostic and therapeutic methods to improve the patient’s life.
The main areas of research focus on the development of precision medicine in pancreatic cancer.

At the translational level, the most important projects focus on the study of the usefulness of liquid biopsy as a method of molecular characterization and biomarker of response to treatment, as well as the generation of organoids as an in vitro model for personalized pharmacological assays. In addition, the group is very active in the field of clinical research.

At the institution we have several clinical trials (phase I, II and III) that offer pharmacological therapeutic alternatives to patients with advanced tumors. Similarly, we have ongoing multicenter randomized studies comparing different surgical techniques in patients with localized tumors. In addition, we collaborate in the development of impact studies on the dissemination of circulating tumor cells during surgery and 3D modeling for liver and pancreatic tumors from standard imaging tests.

Main publications in pancreatic cancer:

  1. Roselló S, Pizzo C, Huerta M, et al. Neoadjuvant treatment for locally advanced unresectable and borderline resectable pancreatic cancer: oncological outcomes at a single academic centre. ESMO Open. 2020; 5(6): e000929. doi: 10.1136/esmoopen-2020-000929
  2. Huerta M, Roselló S, Sabater L, et al. Circulating Tumor DNA Detection by Digital-Droplet PCR in Pancreatic Ductal Adenocarcinoma: A Systematic Review. Cancers (Basel). 2021 Mar; 13(5): 994. doi: 10.3390/cancers13050994
Andres Cervantes
Luis Sabater

Principal Investigator

Group members

  • Andrés Cervantes 
  • Luís Sabater
  • Marisol Huerta Álvaro 

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